spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 7


Fig. 7. Notexin injection after irradiation restores RF expansion. (A) Experimental design of irradiation and notexin treatments in TA muscles of mdx mice. (1) Irradiation only; (2) notexin treatment only; and (3) notexin treatment 4 weeks after 18 Gy irradiation at 3 weeks of age. IHC, immunohistochemistry. (B) The irradiated TA muscle shows a single RF, in contrast to the untreated control TA muscle and notexin-injected muscles without irradiation (notexin only). A regenerating RF cluster reappears after notexin injection in pre-irradiated muscles (18 Gy + notexin). Bar, 100 µm. (C) The total number of RFs and the maximal number of RFs per cluster in TA muscle after notexin treatment with or without pre-irradiation. *Significant difference (P<0.05) was obtained between control mice treated with 18 Gy irradiation only and the mice treated with notexin after 18 Gy pre-irradiation. Each point is the mean ± s.e.m. of 3-4 muscles per group.





Right arrow Return to article