spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 8


Fig. 8. ICP0 is sufficient to redistribute ATRIP in transfected cells. Vero cells were transfected with an expression plasmid encoding the ICP0 gene (pICP0) and fixed in 4% PFA as described in the Materials and Methods. (A) Merged image of a transfected cell double labeled with mouse anti-ICP0 (green) and rabbit anti-P-RPA (red). No colocalization of the two proteins was observed. (B) Merged image of a transfected cell double labeled with rat anti-Hsc70, a cellular marker that stains the interior of ICP0 inclusions (green), and mouse anti-ATRIP (red). Note the ATRIP-stained ICP0-like nuclear inclusions surrounding Hsc70. (C) Merged image of a transfected cell double labeled with mouse anti-ICP0 (green) and rabbit anti-ATR (red). No colocalization of the two proteins was observed. 100x magnification with 2x zoom.





Right arrow Return to article