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Figure 6


Fig. 6. (A) Arr-2 is required for the stability of TRPL channels. Representative immunoblot of TRPL, eye-PKC (PKC), rhodopsin (Rh1), and inositol polyphosphate 1-phosphatase (IPP) in newly eclosed (0d) and 10 day old (10d) dark-raised wild type (WT) and arr25 mutant (arr25). In arr25 mutants is an age-dependent decline in the steady-state level of TRPL protein. By contrast, levels of eye-PKC and rhodopsin remain constant in wild type and arr25 mutant. Anti-IPP was used on all blots as a loading control. Representative immunoblot from a total of 20 different experiments.





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