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Fig. 5. Dephosphorylation of an endosomal pool of PtdIns3P by MTMs. HeLa cells were transfected with MTM1 (A-C), MTMR2 (D-F), MTMR3 (G-I), MTMR4 (J-L), fixed and endosomal PtdIns3P was detected using a biotinylated-GST-2xFYVE protein. Control cells are shown in N and wortmannin-treated cells in M. Bars, 10 µm.
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