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Figure 7


Fig. 7. KCNQ4 and prestin expression in OHCs of heterozygous TR{alpha}1m/+ mutants at P13. (A,B) In OHCs of TR{alpha}1+/+ wild type, expression and distribution of KCNQ4 (A, red) and prestin (B, red) is normal. (C,D) In OHCs of TR{alpha}1m/+ mutants KCNQ4 is completely absent (C) whereas prestin expression and distribution is normal (D). (E,F) By contrast, KCNQ4 expression in vestibular hair cells (VHC) is normal within the same sections of both the wild type (E) and TR{alpha}1m/+ mutants (F). Sections were co-immunolabeled with synaptophysin (green) and DAPI (blue). Bar, 20 µm.





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