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Figure 6


Fig. 6. Crest cell response to LN-1 is mimicked by antibodies against {alpha}1ß1 integrin adsorbed to the substrate. (A-C) Adhesion, spreading and migration on LN-1 and antibodies against {alpha}1ß1 or {alpha}6ß1 integrin. (D,E) Morphology and migration of crest cells on antibodies against {alpha}1ß1 and {alpha}6ß1 at 50 µg/ml. Bar, 100 µm; nt, neural tube. (F) Cell survival on LN-1 at 25 µg/ml (squares) and on antibodies against {alpha}1ß1 (triangles) and {alpha}6ß1 (circles) at 1, 10 and 50 µg/ml. (G,H) Morphologies of crest cells cultured for up to 48 hours on antibodies against {alpha}1ß1 or {alpha}6ß1 at 50 µg/ml. Note the presence of neurons on the antibodies against {alpha}1ß1.





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