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Figure 6


Fig. 6. Pex19p translocates to peroxisomes in a PMP-independent manner. (A) HA2-Pex19p was expressed in CHO-K1 cells (a,b) and CHO mutants, pex14 ZP161 (c,d), pex26 ZP167 (e,f) and pex3 ZPG208 (g,h). Cells were stained with antisera to HA (left panels) and PMP70 (right panels). (B) Fibroblasts from a normal control (a,b) and PBD patients defective in PEX12 (CG3) (c,d), PEX3 (CG-G, CG12) (e,f), and PEX16 (CG-D, CG9) (g,h) were transfected with HA2-PEX19. Cells were stained with antibodies against HA (left panels) and Pex14p (right panels). Bar, 20 µm.





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