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Figure 8


Fig. 8. Distinct intracellular localization of EGFP-R664X AE1 and EGFP-{Delta}F508-CFTR in HEK293 cells treated with lactacystin. Cells were transiently transfected with EGFP-R664X AE1 (EGFP-RX) or EGFP-{Delta}F508-CFTR (EGFP-{Delta}F508) and incubated with (B,C) or without (A) 10 µM lactacystin for 8 hours, and the intracellular localization of EGFP-tagged proteins was compared with that of calnexin (A,B) and ubiquitin (C). Bars, 10 µm.





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