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Figure 4


Fig. 4. Effects of cAMP on the destruction of mycobacteria as viewed by CFU plating assay. (A) M. smegmatis survival. Results represent mean ± s.d. from three independent experiments. (B) M. tuberculosis H37Rv survival. Reagents were added as follows: 8-Br-cAMP (50 µM) added at 3 hours and 2 days post infection. SQ22536 (50 µM) added at 3 hours and 2 day post infection. H-89 (10 µM) added at 3 hours post infection. Asterisks indicate significance as determined by the Student's t-test: *P<0.01 compared with levels in the control.





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