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Figure 2


Fig. 2. Kinesin-13 molecular architecture. (A) Kinesin-13 domain organisation. The same colour scheme of the neck+motor region is used throughout the figures. (B) Sequence alignment of neck+motor constructs of select kinesin-13 motors with the motor core from human kinesin-1. The nucleotide-binding motifs, N1-N4, are as described by Sablin et al. (Sablin et al., 1996). The alignment was performed using T-Coffee (Notredame et al., 2000) and visualised using ESPript (http://espript.ibcp.fr/ESPript/ESPript/index.php). Sequences used: Homo sapiens kinesin-1, X65873; Homo sapiens MCAK, Q99661; Homo sapiens KIF2A, O00139; Drosophila melanogaster KLP59C, AE003459; Drosophila melanogaster KLP10A, AE003485; Plasmodium falciparum PFL2165w, AE014851.





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