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Fig. 1. Cell migration of CD19+ bone marrow and spleen-derived cells from CD24–/– and CD24+/+ mice. (A) CD19+ B-lymphocytic cells from the bone marrow and spleen of CD24–/– and control C57BL/6 mice were isolated using magnetic beads. An aliquot of cells was used for FACS analysis of CD24 and CD45 expression. A CD24 isotype control antibody was also used. (B,C) Chemotactic cell migration of CD24–/– versus CD24+/+ B lymphocytes from the bone marrow (B) and spleen (C) in response to SDF-1. *P≤0.035; **P≤0.02.





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