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Fig. 6. Freeze-fractured nuclear membrane in a lipid-laden macrophage after immunogold labeling (18 nm gold) for adipophilin. The P-face of the outer nuclear membrane (N) is prominently labeled. The E-face of the outer nuclear membrane, and both fracture faces of the inner nuclear membrane are typically devoid of label. The periphery of cross-fractured lipid droplets (LD) and the P-face of the plasma membrane (PL) are also labeled. Bar, 0.5 µm.