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Fig. 3. Mapping of the versican-binding domain in TSP1. (A) [¹²⁵I]-TSP1 binding to immobilized VG1 was determined in the presence of divalent cations and the indicated concentrations of full length TSP1 ( $bullet$ ), NoC1 ( ${circ}$ ), CP123 ( ${triangleup}$ ), P3E123 ( ${diamond}$ ), or E3CaG ( ${square}$ ). (B) A structural model of TSP1. (C) [¹²⁵I]-TSP1 binding to immobilized VG1 was determined in the presence of divalent cations and the indicated concentrations of NoC1 ( $bullet$ ), NoC2 ( ${circ}$ ), E3CaG ( ${blacksquare}$ ), or N ( ${diamondsuit}$ ).

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