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Figure 1


Fig. 1. Localization of the ß-galactosidase reaction product in 5.5-week-old nestin-cre/ROSA26 mice. (A) At low power, the blue reaction product is evident in the retina, lens and ciliary body. Owing to the heavily pigmented PE and iridal epithelial cells, the reaction product is difficult to see in these locations. (Inset A) Control specimen showing no reaction product. (B) At higher magnification, ß-galactosidase activity is clearly visible in the NPE cells (black arrows) and, with favorable planes of section, in the PE cells (white arrows). The zonular fibers joining the ciliary body to the lens are indicated.





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