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Figure 11


Fig. 11. A representative example of the PE/NPE interface in nestin-cre+/Cx43+/flox (A) and nestin-cre+/Cx43flox/flox (B) ciliary bodies of 2.5-week-old animals. In the heterozygote, gap junctions between PE and NPE are very frequent, as indicated by the black arrows. Less frequently, gap junctions can also be observed between NPE cells (white arrows). In the homozygote, gap junctions are not observed at the PE/NPE interface. As described in Fig. 10, tight junctions (TJ) can also be seen limiting the diffusion of HRP between the NPE cells (asterisks).





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