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Figure 6


Fig. 6. Immunohistochemistry of the pancreatic islet of oc/oc mice with anti-a3 and anti-insulin antibodies. (A) Paraffin sections of pancreatic islets from wild-type and oc/oc mice were stained with anti-insulin and anti-a3 antibodies. The morphologies and sizes of islets in wild-type and oc/oc mice were indistinguishable. The insulin contents of ß-cells in the islets were comparable. The lack of a3 expression in oc/oc islets was also confirmed. Bar, 50 µm. (B) Electron micrographs of representative areas of ß-cells from wild-type and oc/oc mice are shown. The dense-core secretory granules (SG) are indicated. Golgi, Golgi apparatus; mt, mitochondria. Bar, 1 µm.





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