spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 2


Fig. 2. Multiple cellular pools of {alpha}-catenin. {alpha}-Catenin exists in multiple cellular pools: incorporated into the cadherin complex at the plasma membrane; as monomers, homo- and hetero-dimers in the cytosol; and potentially also in the nucleus. Both in the cytosol and in the nucleus, cadherin-independent {alpha}-catenin may regulate ß-catenin signalling in the canonical Wnt pathway by forming heterodimers with ß-catenin. {alpha}, {alpha}-catenin; ß, ß-catenin; Dsh, dishevelled; Pygo, Pygobus; TCF, T-cell factor.





Right arrow Return to article