spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 4


Fig. 4. Transplantation of newt cardiomyocytes into regenerating limbs results in a rapid downregulation of heart-muscle-specific genes. (A-L) DiI-labeled cardiomyocytes (A-F, red) were transplanted into a regenerating limb 5 days after amputation and staining for desmin (G-I, green) or MyHC (J-L, green) after 1, 7 and 28 days. Newt cardiomyocytes maintained the expression of the intermediary filament protein desmin in the majority of transplanted cells but rapidly lost the expression of MyHC (MF20 staining; note that MF20 detects both skeletal and cardiac MyHC isoforms). After 28 days, transplanted cells re-expressed MyHC. (M-O,P-R) Mergend images. Bars, 100 µm.





Right arrow Return to article