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Figure 9


Fig. 9. Modulation of the respiratory motor output in vivo after modification of contacts between ER and mitochondria. Shown are the effects of 5 µM nocodazole (A) and 0.1 µM taxol (B). The two traces in each panel present the respiratory motor output ({int}XII) and the membrane current (Im) recorded at the holding potential of -40 mV. The episodes marked by asterisks are expanded in the lower part of each panel. Note differential effects of nocodazole and taxol on the inhibitory and excitatory synaptic currents (the upward and downward deflections in current traces, respectively) and synaptic drives, which represent a correlate of respiratory motor activity.





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