spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 9


Fig. 9. The potential of the DP tail to become codistributed with the desmin network is affected by sequences contained within the rod and tail domains of desmin. Intermediate-filament-free SW13 cells were transiently co-transfected with the cDNAs encoding DP BCS2849G, Myc-tagged at the N-terminus (B,D,F) and tailless desmin (Desmin{Delta}T) (A,C), or desmin I451M (E). Although in most transfected cells, DP and tailless desmin were found together in spot-like and large cytoplasmic aggregates (C,D), in ~5% of the transfected cells the recombinant DP-BCS2849G was found diffusely distributed in the cytoplasm without obvious colocalization with tailless desmin (A,B). In a few cells expressing both desminI451M and DP-BCS2849G, DP-BCS2849G did not become coaligned with desminI451M, but retained a cytoplasmic distribution (E,F). Bar, 20 µm.





Right arrow Return to article