QUICK SEARCH:   [advanced] Author: Keyword(s):
Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents

Help viewing high resolution images Return to article

Fig. 3. Phenotypes of the Drosophila mutants klarsicht and Msp-300^SZ-75. (A) In the wild-type eye imaginal disc, passage of the morphogenetic furrow (MF) initiates the differentiation of photoreceptors. Normally, the nuclei (black circles) are pulled up to the apical side through an association with the centrosome and MTs. In the klarsicht mutant flies, the centrosomes are no longer attached to the nuclei. As a result, the nuclei remain at the basal side. (B) At the start of stage 10B in wild-type Drosophila ovaries, the nurse cells (NCs) start to dump their cytoplasmic contents into the oocyte through the ring canals. By stage 13, most NCs, and their nuclei (large black ovals), have disappeared and the dorsal appendages are extruded at the anterior end. In Msp-300^SZ-75 flies, the NC nuclei become detached once cytoplasmic dumping occurs and either form multi-nucleated cells, enter the oocyte or become mispositioned within individual cells. The germinal vesicle (GV) (the oocyte nucleus) (grey oval) is also mispositioned. For simplicity, only some of the NCs are depicted. A, anterior; P, posterior.

Return to article