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Fig. 2. cdi as a suppressor of the activated Sev pathway. (A) Semi-thin section from a control eye (left) where UAS-cdi is not overexpressed (UAS-cdi/UAS-cdi; sevS11/+) and an experimental eye (right) where the UAS-cdi is overexpressed by sev-Gal4 (UAS-cdi/UAS-cdi; sev-Gal4 sevS11/+). The histogram shows distribution profiles of the number of R7 photoreceptors per ommatidium for each genotype represented. The statistical analysis reveals significant differences between the genotypes (P<0.001). (B) Semi-thin section of control eye (left), where UAS-Boss is expressed under sev-Gal4 (UAS-Boss/+; sev-Gal4/+) and experimental eyes (UAS-cdi/UAS-Boss; sev-Gal4/+) are shown. The histogram quantifies the number of R7 per ommatidium with and without cdi overexpression (P<0.001). The inset below shows two ommatidia from a UAS-cdi/UAS-cdi; sev-Gal4 fly, one with R7 (right) and one without (left). R7 rhabdomeres are colored green.