spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 6


Fig. 6. Constitutive Ser125 phosphorylation negatively regulates Runx2-mediated expression of osteoblastic genes. Primary dermal fibroblasts were transduced with Runx2-WT, Runx2-125Gly or Runx2-125Glu retrovirus and cultured in osteogenic media with (+) and without (–) 10 nM DEX. mRNA levels were investigated by quantitative RT-PCR at 7 days post-transduction [mean + s.e.m., n=6; ANOVA: P<1E-6; {dagger}different from Runx2-DEX, ¥different from 125Gly-DEX, §different from 125Glu-DEX and 125Glu+DEX, £different from 125Glu-DEX (P<0.05)]. Relative gene expression is expressed on a logarithmic scale.





Right arrow Return to article