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Fig. 6. Fibroblast-embedded collagen gels were prepared and cast in the absence (control) or presence of 10 µM ß-AR agonist, 50 µM rp-cAMP, or both 10 µM ß-AR agonist and 50 µM rp-cAMP. The diameters of the collagen gels were measured after 24 hours and the percentage collagen gel contraction calculated; maximum contraction (1.5 cm) was considered as 100%. Values represent mean ± s.e.m. (n=6). *P<0.01 between ß-AR agonist and controls, #P<0.05 between rp-cAMP/ß-AR agonist and ß-AR agonist. Results were combined from three independent experiments from at three dermal fibroblast strains.