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Figure 6


Fig. 6. The single-enzyme disorder, D-BP deficiency, is also characterized by decreased cellular peroxisome abundance and distribution along peripheral microtubules. (A) Peroxisome abundance and distribution along microtubules in HSFs from a D-BP-deficient patient. (B) Confocal laser-scanning microscopic image of a D-BP-deficient cell showing alignment of residual peroxisomes with microtubules. (C) Abundance and distribution of peroxisomes along microtubules in HSFs from an X-ALD patient. PEX14, green; {alpha}-tubulin, red. Bars, 20 µm.





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