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Figure 7


Fig. 7. PEX11ß-myc overexpression leads to remnant peroxisome proliferation and redistribution along microtubules in PEX1-null and D-BP deficient cells. (A-C) PEX1-null and (D-F) D-BP-deficient patient HSFs stably expressing human PEX11ßmyc. For epifluorescence microscopy, cells were double-labeled with PEX14 antibody (red) and myc antibody (green) (A,B,D,E). Panels B and E are magnifications of regions shown in overlay panels in A and D, respectively. For confocal laser-scanning microscopy, cells were double-labeled with PEX14 antibody (green) and {alpha}-tubulin antibody (red) (C and F). Bars, 20 µm (A,C,D,F); 5 µm (B,E).





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