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Figure 8


Fig. 8. Par-1 act upstream of Notch in eye disc cell determination. Antenna-eye disc complexes were stained to identify cell nuclei (red) and for neuron-specific Elav (green), which marks differentiating eye tissue but not the antenna disc. (A-C) ey-Gal4 UAS-Par-1 complexes have a smaller eye disc, no eye disc, or transformation of an eye disc into an antenna disc. (D) ey-Gal4 UAS-Par-1(AA) disc complex shows normal determination. (E) ey-Gal4 UAS-Nintra disc complex shows development of extra eye tissue. (F) ey-Gal4 UAS-Nintra UAS-Par-1 disc complex shows development of extra eye tissue. This hyperplasia is significantly enhanced compared to E.





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