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Figure 6


Fig. 6. Agonist-induced oscillations in levels of Ca2+ and cAMP. (A) Single-cell cytosolic Ca2+ changes in response to 10 µM CCh showing either (i) sustained Ca2+ increase or (ii) regular Ca2+ oscillations. (B) Parallel experiments measuring cAMP signals in individual Epac-1-probe- and AC8-expressing cells with and without external Ca2+. 10 nM PGE1 was present throughout the period of CCh application.





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