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Figure 1


Fig. 1. Sequence comparison of hFBNRG3 and hNRG3. (A) Alignment of the hFBNRG3 and hNRG3 transcripts to the human genome by BLAST search. Exon 1 is spliced out in hFBNRG3, whereas exons 2 and 3 are spliced out in the hNRG3 transcript. Exons 4 to 11 are shared by both transcripts. (B) Predicted aa sequences for both transcripts are compared. EGF-like domains and transmembrane segments are indicated, and also the N-terminal hydrophobic segment for hFBNRG3. Both polypeptides diverge completely in the N-terminal domain and are preserved from the EGF-like to C-end. Perfectly conserved aa are underlined with asterisks.





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