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Figure 7


Fig. 7. Density of spines is the same in NP+/+ and NP-/- mice. (A) Fluorescence images of hippocampal CA1 pyramidal neurons of NP+/+ (left) and NP-/- mice (right) after injection of Lucifer Yellow. Arrowheads denote areas enlarged in B: proximal (prox.) (a and d), middle (mid.) (b and e) and distal (dist.) (c and f). (B) Spine morphology of NP+/+ (left) and NP-/- (right) mice in prox. (a and d), mid. (b and e) and dist. (c and f) regions. Images are from the regions marked by the respective arrowheads in A. Bar, 5 µm. (C) Spines were counted in NP+/+ (open bars) and NP-/- (closed bars) mice. The left graph shows the density of spines in the stratum radiatum, and the right graph shows that in each region according to the distance from the CA1 soma. There was no difference in the density of spines between NP+/+ and NP-/- mice.





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