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Figure 3


Fig. 3. Cell-mediated shunting and exchange of fibrillar material. Time-lapse image series showing examples of cell-mediated `shunting' of fibrillar ECM material and `exchange' of fibrillar material from one fibril to another. The image series shows an enlargement of fibrils C and D from Fig. 1. Fibril C moves upwards and to the left and by 4 hours, becomes joined with another fibril indicated by the white arrowhead. Fibril D appears joined at zero hours with a fibril indicated by the open arrowhead. By 1 hour 30 minutes, fibril D has detached from this fibril. It then retracts and moves upwards and to the left to become joined to a different fibril, indicated by the open arrow. See Movie 3 in supplementary material. Bar, 50 µm.





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