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Figure 8


Fig. 8. Model of the hypothetical role of the nELAV RBPs during neurogenesis. In the temporal sequence of events that lead a proliferating NSC to become a differentiated neuron, Msi1 and nELAV RNA-binding activities are complementary and exert a different function on their target mRNAs. nELAV stabilization of the Msi1 transcript may prolong its expression during the gradual passage from proliferation to differentiation.





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