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Fig. 1. GIT1 and GIT2 domain structure. The full-length GIT proteins have an N-terminal ARF GTPase-activating protein (ARF-GAP) domain, three ankyrin (ANK) repeats, a Spa2-homology domain (SHD), a coiled-coil (CC) domain and a paxillin-binding site (PBS). The truncated GIT2-short protein lacks the CC domain and PBS.
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