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Figure 3


Fig. 3. Microtubules are required for cathodal turning. (A) Mean angle turned in 3 hours; n, number of growth cones; noc, nocodazole; tax, taxol; vin, vinblastine. *P<0.05; **P<0.005; ***P<0.0001. Black asterisks indicate comparison with `DMSO + EF' (for noc and tax) or `no drug + EF' (for vin), and grey asterisks indicate comparison with `DMSO no EF' control or `no drug, no EF' control. (B) Mean rate of growth cone advance. (C) Frequency of turning towards the cathode (filled bars) or anode (open bars) during 3 hours. #P<0.002; ##P<0.001. (D) Composite drawings made from images of individual neurons at the end of 3 hours. Cell bodies have been superimposed and individual neurite paths traced. Bar, 100 µm, applies to all.





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