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Fig. 3. Endothelial cell stiffness (elastic modulus) in living HUVEC. Cells were exposed for 72 hours to solvent (control), to aldosterone (aldo), to aldosterone and spironolactone (aldo+spiro), to dexamethasone (dexa), or to dexamethasone and RU486 (dexa+RU). Mean values ± s.e.m. are shown; the number of individual cells in which stiffness was measured is shown in the bars. Asterisk indicates significant difference in comparison with control (P<0.01).