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Figure 4


Fig. 4. (A) Transendothelial dextran permeability measured with fluorescence-labeled 40 kDa dextran. Cells were exposed for 72 hours to solvent (control), to aldosterone (aldo), to aldosterone and spironolactone (aldo+spiro), to dexamethasone (dexa), or to dexamethasone and RU486 (dexa+RU). Mean values ± s.e.m. are shown; the number of measurements on individual monolayers is shown in the bars. Asterisk indicates significant difference in comparison with control (P<0.01); § indicates significant difference in comparison with dexamethasone (P<0.02). (B) Transendothelial electrical resistance measured with the electrical cell impedance sensing (ECIS) technique. Cell treatment was as described in section A. Mean values ± s.e.m. are shown; the number of measurements on individual monolayers is shown in the bars. Asterisk indicates significant difference in comparison with control (P<0.01).





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