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Figure 3


Fig. 3. Large pericentromeres colocalize more frequently with H3S10P foci than small pericentromeres. (A-C) Immuno-FISH images display pericentromeres of human chromosome 1 (A), chromosome 2 (B) and chromosomes 14 and 22 (C) in NT2 nuclei exhibiting fewer than ten (a-d), or more than ten H3S10P foci (e-h). Bar, 10 µm. (D) Percentage of phospho-H3 positive pericentromeres in populations of NT2 nuclei exhibiting phospho-H3 foci is shown for seven human chromosomes, as indicated. The number of FISH signals analyzed is indicated for each chromosome (with legends).





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