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Figure 2


Fig. 2. Multiple pathways of ciliogenesis. Quiescent somatic cells use a single pre-existing mature centriole to subtend a transient primary cilium (Fig. 1 and Figure 2) lacking central pair microtubules, which is lost as the cell re-enters the cell cycle. In differentiated cells, several different types of single cilia can be produced from a mature centriole, such as the temporary (9+2 or 9+0) kinocilium (Figure 2), which may or may not possess the central pair microtubules (Flock and Duvall, 1965; Sobkowicz et al., 1995) and the primary (9+0) cilium produced on the luminal epithelium of kidney tubules (Figure 2). The pathways that produce several hundred cilia in epithelial cells in the mammalian airway are depicted at Figure 2 and Figure 2. Here, hundreds of centrioles are produced, duplicated either using the pre-existing centriole as a template (Figure 2), or formed via a non-templated method (Figure 2). The sperm flagellum produced in male meiosis is depicted at Figure 2. Green denotes 9+2 axonemes; dark blue denotes 9+0 axonemes; centrioles are shown in red; the deuterosome is shown in purple.





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