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Figure 8


Fig. 8. The migration of implanted OECs is facilitated by neutralizing NgR in a spinal cord hemisection injury model. (A) The animals implanted with DiI-labelled OECs were treated with N.S., anti-NgR antibody or goat IgG every day through a pipe embedded in the subarachnoid space. After 10 days, the length, width and area of the region invaded by DiI-postive cells were measured by using MetaMorph Imaging System analysis software. The three right panels are locally magnified images of the three left panels. (B) Quantitative assessment of cell migration in vivo. Migration Index (%)=Maximum length, width or area traveled by DiI-positive cells in the presence of anti-NgR antibody or irrelevant IgG as a percentage of the maximum length, width or area traveled by DiI-positive cells in the presence of N.S. **P<0.01 versus N.S. Bar, 50 µm.





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