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Figure 7


Fig. 7. Dvl2 accelerates the recruitment of axin into dynamic protein assemblies. (A,B) Graphs of FRAP experiments conducted in COS-7 cells, in which individual (A) axin-GFP or (B) Dvl2-GFP puncta were bleached, and fluorescence recovery within the bleached boxes was monitored every 5 seconds (coloured lines represent different puncta; values were normalised with respect to unbleached control puncta, shown by dotted line). (C-G) Graphs of FRAP experiments of axin-GFP as in A, but in the presence of co-expressed wt or mutant Dvl2, as indicated. Note that wt but not mutant Dvl2 accelerates the recovery rates of axin-GFP.





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