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Figure 1


Fig. 1. Temporal and spatial patterns of Abcg2 expression in the developing retina. (A,B) RT-PCR analysis carried out on cDNA obtained from different stages of late retinal histogenesis and adult retina revealed that levels of transcripts corresponding to ABCG2 decreased as differentiation progressed. (C,D) ABCG2 immunoreactivity in a PN1 retinal section is predominantly confined to the outer neuroblastic layer. (E,F) In dissociated PN1 retinal cells pre-exposed to BrdU, ABCG2 is expressed in cells that also incorporated BrdU (arrows). ONbL, outer neuroblastic layer. IR, inner retina. Magnification, 200x.





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