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Figure 7


Fig. 7. Effects of expressing PrPC on HttQ103 aggregation and proteasome activity in neuronal (SN56) and non-neuronal cells (HeLa and CHO). (A) Effect of overexpression of PrPC on the extent of HttQ103 aggregation in different cell types. (B) Effect of overexpression of PrPC on proteasome activity in different cell types. In addition to HttQ103, cells were co-transfected with the same concentration of either pcDNA4 or PrPC expressing vector, as indicated. *P<0.01 compared with cells transfected with only HttQ103.





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