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Fig. 5. (A,B) Localization of 
-catenin phosphorylated on residues 33, 37 and 41 in control cells (A) and in cells exposed to shear stress (B). (C,D) Localization of -catenin phosphorylated on residues 41 and 45 in control cells (C) and in cells exposed to shear stress (D). (E,F) Cells were transfected with -catenin mutated on residues 33 and 37 and with TOPFLASH (E) or with a –163 cyclin D1 reporter (F) and exposed to shear stress for 16 hours. (G) HCT116 cells, which express -catenin missing serine 45, were transfected with TOPFLASH and exposed to shear stress for 12 hours.
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