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Figure 4


Fig. 4. Nuclear distribution of DDB2 after global UV exposure. (A,B) Representative confocal images of DDB2-EYFP cells (C-E) Example of a DDB2-EYFP cell (C) that was transfected with cerulean-histone H2A (D); the merged images of the two signals is shown in E. (K) Line scan along the arrow in E. (F,G) Representative confocal images of DDB2-EYFP cells that were exposed to global UV-C irradiation (16 J/m2). (H-J) Globally UV-irradiated DDB2-EYFP expressing cell (H) that was transfected with cerulean-histone H2A (I); the merged images of the two signals is shown in J. (L) Line scan along the arrow in J. (M) Example of a cell expressing DDB2-EYFP, that was globally UV-C irradiated (16 J/m2) in metaphase and monitored until cell division was completed.





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