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Figure 6


Fig. 6. ZRP-1-depleted cells show altered collective cell migration. HeLa cells treated with control siRNA or ZRP-1 siRNA were subjected to wound-healing assay as described in Materials and Methods. Four hours after wounding, cells were imaged at 1-minute intervals for 12 hours. (A) Images of ZRP-1-depleted cells and control cells at 4, 7, 10 and 16 hours after wounding. (B) Percentages of the wound area that has been filled in by migrating cells at each time point. The mean percentages of three independent experiments are shown. Black and white circles indicate ZRP-1-depleted cells and control cells, respectively; error bars indicate standard deviations.





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