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Figure 4


Fig. 4. Crumbs mislocalization precedes the loss of Bazooka and Armadillo in Exo84 mutants. (A-D) Crumbs (green), Bazooka (blue) and Armadillo (red) in stage 9 wild-type (A), Exo84 (B), arm (C) and shg (D) mutant embryos. (A) In the wild type, Crumbs, Bazooka and Armadillo localize apically. (B) At the onset of epithelial disruption in Exo84 mutants, Armadillo localizes apically whereas Crumbs is absent from large areas. The degree of apical Bazooka localization is intermediate. (C,D) In arm and shg mutants, Crumbs and Bazooka are absent in regions lacking Armadillo. Anterior, left; ventral, down. Bar, 10 µm.





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