spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 1


Fig. 1. ZBP1 expression causes phenotypic conversion from random walk to directed movement, increasing persistence and directionality. Movement of GFP- and GFP-ZBP1-expressing MTLn3 cells (from two independently derived stable cell lines, indicated as ZBPA and ZBPB) was examined in 5% serum. The total time interval was 30 minutes, and time between successive frames was 1 minute. (A,B) Plots of cell (A) centroid and (B) perimeter for six GFP-expressing control MTLn3 cells (CTRL, A and B top) and six GFP-ZBP1-expressing MTLn3 cells (ZBP, A and B bottom). (C,D) Differences in (C) persistence and (D) directionality were statistically significant between the populations (*P<0.005, error bars indicate ± s.e.m.). Persistence is the speed divided by the change in direction, directionality is the net path length divided by the total path length.





Right arrow Return to article