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Figure 1


Fig. 1. Cdc42 is enriched at the apical neuroblast cortex. (A) Wild-type central brain neuroblasts 120 hours after larval hatching (ALH). Normal apical and basal protein localization and phosphorylated histone H3 (PH3) are shown with background Myc staining. (B-E) cdc42-3 central brain neuroblasts at 96 hours ALH expressing Cdc42-Myc under its native promoter (cdc42-3; cdc42:myc). All stages of mitosis are represented. Arrowheads delineate extent of aPKC (aPKC PH3) and Cdc42-Myc (Cdc42:myc) apical crescents.





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