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Figure 5


Fig. 5. Inhibitors link PML bodies to protein degradation and trafficking. Top four panels: Primary WI-38 cells were treated with either 10 µM MG132 or 1 µM LMB or both for 2 hours, allowing co-localization of ubiquitin (green) and PML (red). LMB panel is a Z-projection of a confocal stack acquisition. Bottom panel: 3D reconstruction of deconvoluted images.





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