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Fig. 4. mDia2 is necessary for normal focal adhesion morphometry. (A) Paxillin immunofluorescence in control, mDia2 antibody-injected (anti-mDia2), dominant negative mutant expressing (
FH2), and mDia1 antibody-injected (anti-mDia1) cells. (B) Control and mDia2 antibody-injected cells expressing GFP-paxillin. (C,D) Average number per cell (C), and size (D) of paxillin stained focal adhesions ± s.e.m., n=12 cells per treatment.